The familiar and the unexpected in structures of icosahedral viruses

Curr Opin Struct Biol. 2001 Apr;11(2):195-9. doi: 10.1016/s0959-440x(00)00189-5.


Viruses were the first large macromolecular assemblages to be visualized at high resolution. New virus structures continue to challenge our understanding of specificity in protein-protein "recognition". The evolution of virus structures has been even more opportunistic than previously imagined.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Biological Evolution
  • Iridoviridae / chemistry
  • Iridoviridae / metabolism*
  • Iridoviridae / ultrastructure*
  • Reoviridae / chemistry
  • Reoviridae / metabolism
  • Reoviridae / ultrastructure