An extremely severe case of cutaneous calcinosis with juvenile dermatomyositis, and successful treatment with diltiazem

Br J Dermatol. 2001 Apr;144(4):894-7. doi: 10.1046/j.1365-2133.2001.04153.x.


A case of cutaneous calcinosis associated with juvenile dermatomyositis is described. The patient was a 3-year-old girl who had been diagnosed as having dermatomyositis at age 1 year. She was treated with prednisolone, but developed multiple calcified nodules in the subcutaneous tissues and intermuscular fascia. These nodules gradually increased in size despite continual therapy with steroids and aluminium hydroxide. Treatment with diltiazem completely suppressed the development of calcinosis.

Publication types

  • Case Reports

MeSH terms

  • Calcinosis / diagnostic imaging
  • Calcinosis / drug therapy
  • Calcinosis / etiology*
  • Calcium Channel Blockers / therapeutic use*
  • Child, Preschool
  • Dermatomyositis / complications*
  • Diltiazem / therapeutic use*
  • Female
  • Follow-Up Studies
  • Humans
  • Radiography
  • Skin Diseases / drug therapy
  • Skin Diseases / etiology*


  • Calcium Channel Blockers
  • Diltiazem