Asymmetric cell division: plane but not simple

Curr Biol. 2001 Mar 20;11(6):R233-6. doi: 10.1016/s0960-9822(01)00113-0.


The polarity of sensory bristles on the thorax of Drosophila is linked to the orientation of the asymmetric cell divisions that partition cell fate determinants in this lineage. The orientation of these divisions is under the control of the Frizzled pathway that generates planar polarity in a number of cell types.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Body Patterning / physiology*
  • Cell Differentiation
  • Cell Division
  • Drosophila / growth & development
  • Drosophila Proteins*
  • Frizzled Receptors
  • Membrane Proteins / metabolism
  • Membrane Proteins / physiology*
  • Receptors, G-Protein-Coupled


  • Drosophila Proteins
  • Frizzled Receptors
  • Membrane Proteins
  • Receptors, G-Protein-Coupled
  • fz protein, Drosophila