Muscle development: reversal of the differentiated state

Curr Biol. 2001 Mar 20;11(6):R237-9. doi: 10.1016/s0960-9822(01)00114-2.

Abstract

Cell fate selection and cell cycle exit are fundamental features of differentiation during animal development. Accumulating data suggest that these processes are more readily reversible than previously supposed and are beginning to point at the underlying molecular mechanisms.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Differentiation
  • Homeodomain Proteins / biosynthesis
  • Homeodomain Proteins / genetics
  • Homeodomain Proteins / physiology*
  • MSX1 Transcription Factor
  • Muscle Fibers, Skeletal / cytology*
  • Myogenic Regulatory Factors / biosynthesis
  • Myogenic Regulatory Factors / genetics
  • Transcription Factors*

Substances

  • Homeodomain Proteins
  • MSX1 Transcription Factor
  • Myogenic Regulatory Factors
  • Transcription Factors