Ciprofloxacin-induced acute renal failure in a patient with cystic fibrosis

Pediatr Infect Dis J. 2001 Mar;20(3):320-1. doi: 10.1097/00006454-200103000-00024.


Acute renal failure is a rare adverse reaction of antibiotic therapy with quinolones seldom seen in young patients. We report an 18-year-old young woman with cystic fibrosis who experienced a pronounced decline in renal function after oral treatment with ciprofloxacin for 3 weeks. Withdrawal of the drug led to normalization of renal function after 10 days.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / chemically induced*
  • Adolescent
  • Anti-Infective Agents / adverse effects*
  • Anti-Infective Agents / therapeutic use
  • Ciprofloxacin / adverse effects*
  • Ciprofloxacin / therapeutic use
  • Creatinine / blood
  • Cystic Fibrosis / complications
  • Female
  • Humans
  • Lung Diseases / drug therapy
  • Pseudomonas Infections / drug therapy


  • Anti-Infective Agents
  • Ciprofloxacin
  • Creatinine