A variation of vitamin D deficiency in children

J Pediatr Endocrinol Metab. 2001 Feb;14(2):203-6. doi: 10.1515/jpem.2001.14.2.203.

Abstract

We report three children presenting with hypocalcemia, hyperphosphatemia, elevated levels of parathyroid hormone, low concentrations of 25(OH)-vitamin D, normal to elevated concentrations of 1,25(OH)2-vitamin D, and normal radiographs. Although these findings led to consideration of parathyroid hormone resistance, clinical and biochemical findings remained normal after discontinuation of therapy, suggesting a variation of vitamin D deficiency.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Calcium / therapeutic use
  • Child, Preschool
  • Female
  • Genetic Variation*
  • Humans
  • Hypocalcemia / complications
  • Hypocalcemia / drug therapy
  • Infant
  • Male
  • Parathyroid Hormone / blood
  • Phosphates / blood
  • Vitamin D / analogs & derivatives*
  • Vitamin D / blood
  • Vitamin D / therapeutic use
  • Vitamin D Deficiency / complications
  • Vitamin D Deficiency / drug therapy
  • Vitamin D Deficiency / physiopathology*

Substances

  • Parathyroid Hormone
  • Phosphates
  • Vitamin D
  • 1,25-dihydroxyvitamin D
  • 25-hydroxyvitamin D
  • Calcium