Prevalence of Low Bone Density in Women With Developmental Disabilities

J Clin Densitom. Spring 2001;4(1):25-9. doi: 10.1385/jcd:4:1:25.


This study was designed to assess the prevalence and severity of low bone mineral density in an institutionalized population of postmenopausal women (n = 79) with developmental disabilities, using quantitative ultrasound of the calcaneus. The results demonstrate that this population has a significantly lower quantitative ultrasound index (QUI) of the calcaneus compared with a referent population of age-matched control subjects without mental disabilities. We used the QUI T-score threshold of <-2.0 standard deviations (SDs) to define individuals at high risk for osteoporosis, and 82% of the study participants met this criterion. Furthermore, approx 43% of the population had a heel QUI that was more than 2 SDs below that of age-matched control subjects, consistent with a severe degree of demineralization.

MeSH terms

  • Autistic Disorder / epidemiology*
  • Calcaneus / diagnostic imaging
  • Calcaneus / physiopathology
  • Cerebral Palsy / epidemiology*
  • Comorbidity
  • Humans
  • Intellectual Disability / epidemiology*
  • Middle Aged
  • New York / epidemiology
  • Osteoporosis, Postmenopausal / epidemiology*
  • Prevalence
  • Ultrasonography