Challenges and opportunities for development of an AIDS vaccine

Nature. 2001 Apr 19;410(6831):1002-7. doi: 10.1038/35073500.


Among the devastating consequences of AIDS has been its epidemic spread in the developing world. The disease has caused unprecedented suffering, debilitation, loss of life and disruption of family, social and economic stability. Because of the considerable expense and logistical difficulty in providing antiviral drugs to populations infected with the human immunodeficiency virus throughout the world, the biomedical community is looking towards vaccines to help solve this compelling problem.

Publication types

  • Review

MeSH terms

  • AIDS Vaccines* / immunology
  • Adjuvants, Immunologic
  • Animals
  • HIV / immunology*
  • HIV Antibodies / biosynthesis
  • HIV Antibodies / immunology
  • HIV Antigens / immunology
  • HIV Infections / immunology*
  • HIV Infections / prevention & control*
  • Humans
  • T-Lymphocytes, Cytotoxic / immunology
  • Vaccines, Attenuated
  • Vaccines, Synthetic


  • AIDS Vaccines
  • Adjuvants, Immunologic
  • HIV Antibodies
  • HIV Antigens
  • Vaccines, Attenuated
  • Vaccines, Synthetic