Relapse pattern of Plasmodium vivax in Mumbai: a study of 283 cases of vivax malaria

J Assoc Physicians India. 2000 Nov;48(11):1085-6.

Abstract

Objectives: To analyze the relapse pattern of Plasmodium vivax in the city of Mumbai.

Methods: 283 cases of smear positive vivax malaria were treated with full dose (25 mg/kg) chloroquine and were asked to follow up for at least one year. None of the patients received primaquine.

Results: Of the 150 cases who followed up for at least one year, 19 relapsed, 17/19 relapsed within the first 6 months; indicating that the relapse pattern in the city is predominantly of the tropical or Chesson strain type.

Conclusions: Vivax malaria patients should be monitored for at least six months. Those who do relapse should receive treatment with full dose chloroquine and 14 days of primaquine treatment.

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Animals
  • Antimalarials / administration & dosage*
  • Chloroquine / administration & dosage*
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • India / epidemiology
  • Malaria, Vivax / diagnosis
  • Malaria, Vivax / drug therapy*
  • Malaria, Vivax / epidemiology
  • Male
  • Middle Aged
  • Plasmodium vivax / isolation & purification*
  • Prospective Studies
  • Recurrence
  • Risk Factors
  • Sex Distribution
  • Treatment Outcome

Substances

  • Antimalarials
  • Chloroquine