Abstract
Objective:
To explore a new method for effective and safe prevention and treatment of caries.
Methods:
Following the theory of tooth remineralization, we searched for the mechanism and clinical application of tooth remineralization with phosphopeptide.
Results:
Phosphopeptide, with calcium and phosphorus, had a high affinity for hydroxyapatite and could enhance tooth remineralization.
Conclusion:
Phosphopeptide was effective in the prevention and treatment of tooth decay. Clinically, it could be safely applied.
MeSH terms
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Animals
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Calcium Phosphates / chemistry
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Calcium Phosphates / therapeutic use
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Cariostatic Agents / therapeutic use*
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Chemical Precipitation
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Dental Caries / prevention & control
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Dental Enamel / drug effects
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Dental Enamel / ultrastructure
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Diet, Cariogenic
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Durapatite / chemistry
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Female
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Hardness
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Humans
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Microscopy, Polarization
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Phosphates / chemistry
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Phosphoproteins / chemistry
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Phosphoproteins / therapeutic use*
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Potassium Compounds / chemistry
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Rats
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Rats, Sprague-Dawley
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Solubility
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Tooth Demineralization / prevention & control
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Tooth Remineralization*
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Toothpastes / therapeutic use
Substances
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Calcium Phosphates
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Cariostatic Agents
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Phosphates
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Phosphoproteins
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Potassium Compounds
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Toothpastes
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alpha-tricalcium phosphate
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tetracalcium phosphate
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calcium phosphate, monobasic, anhydrous
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Durapatite
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calcium phosphate
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potassium phosphate
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calcium phosphate, dibasic, anhydrous