Vancomycin anaphylaxis in a patient with vancomycin-induced red man syndrome

Am J Ther. 2000 Sep;7(5):319-20. doi: 10.1097/00045391-200007050-00010.


Vancomycin is a powerful glycopeptide antibiotic that is increasingly being used owing to the emergence of highly resistant organisms such as methicillin-resistant Staphylococcus aureus. Although a generally safe medication, administration of vancomycin is not benign, and there have been a number of adverse reactions reported. We present the case of a patient with vancomycin-induced red man syndrome who developed vancomycin anaphylaxis. Our case illustrates that red man syndrome may be a marker for true vancomycin allergy, although it was generally not thought of as so in the past.

Publication types

  • Case Reports

MeSH terms

  • Anaphylaxis / chemically induced*
  • Anti-Bacterial Agents / adverse effects*
  • Drug Hypersensitivity / etiology
  • Female
  • Humans
  • Middle Aged
  • Pruritus / chemically induced
  • Vancomycin / adverse effects*


  • Anti-Bacterial Agents
  • Vancomycin