Nephrotic edema

Semin Nephrol. 2001 May;21(3):262-8. doi: 10.1053/snep.2001.21654.


This article starts with a concise synopsis of the history of edema. The role of underfilling, overflow, antidiuretic hormone, and acquaporins is subsequently discussed. Emphasis is given to the use of diuretics in edematous patients. The role and risks of albumin infusion are illustrated. The new hypothesis of pulse reverse osmosis is discussed. The final section deals with the measurement of colloid osmotic pressure in the clinical setting.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Edema / physiopathology*
  • Edema / therapy*
  • Humans
  • Kidney / physiopathology
  • Kidney Diseases / physiopathology*
  • Kidney Diseases / therapy*
  • Nephrotic Syndrome / physiopathology
  • Nephrotic Syndrome / therapy