Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. Mar-Apr 2001;23(2-3):203-6.
doi: 10.1179/016164101101198343.

Gene Expression in Neurotrauma

Affiliations
Review

Gene Expression in Neurotrauma

S A Dutcher et al. Neurol Res. .

Abstract

It has been established that following injury to the central nervous system two types of damage take place, the initial insult and the secondary response to injury. This review will focus on the secondary molecular aspects of neurotrauma. These responses may be either deleterious or have protective effects upon the injured cell population. Molecular responses include the regulation of genes which change cellular architecture, up-regulate of growth factors, induce reparative stress responses, influence apoptosis and regulate the transcriptional process. The purpose of this study is to provide the reader with a brief overview of some of the molecular mechanisms which are activated following a neurological insult.

Similar articles

See all similar articles

Cited by 1 article

LinkOut - more resources

Feedback