Choroidal neovascularization in myopic eyes after laser-assisted in situ keratomileusis

Retina. 2001;21(2):115-20. doi: 10.1097/00006982-200104000-00003.


Purpose: To analyze the appearance and characteristics of choroidal neovascularization (CNV) in patients with high myopia corrected by laser-assisted in situ keratomileusis (LASIK).

Patients and methods: The authors studied CNV in 2955 consecutive eyes (1632 patients) that underwent LASIK for the correction of myopia (from -6 to -27.5 diopters). Follow-up was 34.2+/-11.3 months.

Results: Choroidal neovascularization occurred in three eyes (0.10%) and in one eye previous CNV was reactivated (three women, one man). The time interval between refractive surgery and CNV was 13+/-9.5 months (range, 4-26 months). Mean best-corrected visual acuity (BCVA) after LASIK and before CNV development was 20/57 (range, 20/100-20/29). After the appearance of CNV, mean BCVA was 20/606 (range, 20/2000-20/80). Differences between BCVA before and after CNV were statistically significant (P = 0.04, paired Student's t-test). The CNV was treated in two cases by argon laser photocoagulation and in two cases by surgical excision of CNV by vitrectomy. The final mean BCVA was 20/277 (range, 20/800-20/50). Differences between BCVA after LASIK and after CNV treatment were statistically significant (P = 0.04, paired Student's t-test).

Conclusions: Laser-assisted in situ keratomileusis as a correcting procedure for myopia was followed by low appearance of CNV. The appearance and treatment of CNV was followed by a significant decrease of BCVA.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Choroidal Neovascularization / etiology*
  • Choroidal Neovascularization / surgery
  • Cornea / surgery*
  • Female
  • Humans
  • Keratomileusis, Laser In Situ / adverse effects*
  • Laser Coagulation
  • Male
  • Myopia / surgery*
  • Prospective Studies
  • Recurrence
  • Risk Factors
  • Time Factors
  • Visual Acuity
  • Vitrectomy