Fluoride content of infant formulas prepared with deionized, bottled mineral and fluoridated drinking water

ASDC J Dent Child. Jan-Feb 2001;68(1):37-41, 10.


Usually infant milk formula is the major source of fluoride in infancy. Fluoride concentrations in ten samples of powdered milk formulas, prepared with deionized, bottled mineral, and fluoridated drinking water were determined after HMDS-facilitated diffusion, using a fluoride ion specific electrode(Orion 9609). Fluoride concentrations ranged from 0.01 to 0.75 ppm; from 0.02 to 1.37 ppm and from 0.91 to 1.65 ppm for formulas prepared with deionized, bottled mineral (0.02 to 0.69 ppm F) and fluorinated drinking water (0.9 ppm F), respectively. Possible fluoride ingestion per Kg body mass ws estimated. With deionized water, only the soy-based- formulas should provide a daily fluoride intake of above the suggested threshold for fluorosis. With water containing 0.9 ppm F, however, all of them would provide it. Hence, to limit fluoride intakes to amounts <0.1 mg/kg/day, it is necessary to avoid use fo fluoridated water (around 1 ppm) to dilute powdered infant formulas.

MeSH terms

  • Animals
  • Body Weight
  • Cariostatic Agents / administration & dosage
  • Cariostatic Agents / adverse effects
  • Cariostatic Agents / analysis*
  • Fluoridation*
  • Fluorides / administration & dosage
  • Fluorides / adverse effects
  • Fluorides / analysis*
  • Fluorosis, Dental / etiology
  • Food Preservation
  • Humans
  • Infant
  • Infant Food / analysis*
  • Ion-Selective Electrodes
  • Milk / chemistry
  • Mineral Waters / analysis*
  • Soybeans
  • Water Supply / analysis


  • Cariostatic Agents
  • Mineral Waters
  • Fluorides