SHV-type extended-spectrum beta-lactamase in a Shigella flexneri clinical isolate

J Antimicrob Chemother. 2001 May;47(5):685-8. doi: 10.1093/jac/47.5.685.


A Shigella flexneri isolate resistant to oxyimino-cephalosporins was recovered from a stool sample of a 16 month-old Algerian child hospitalized in Paris, France. This isolate harboured an SHV-2 beta-lactamase gene located on a c. 80 kb self-transferable plasmid. This is the first report of an Ambler class A extended-spectrum beta-lactamase from Shigella spp.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Base Sequence
  • DNA, Bacterial / analysis
  • Humans
  • Infant
  • Microbial Sensitivity Tests
  • Molecular Sequence Data
  • Shigella flexneri / drug effects
  • Shigella flexneri / enzymology*
  • Shigella flexneri / genetics
  • beta-Lactamases / genetics
  • beta-Lactamases / metabolism*


  • Anti-Bacterial Agents
  • DNA, Bacterial
  • beta-lactamase SHV-2
  • beta-Lactamases

Associated data

  • GENBANK/AF096930