Molecular targets for breast cancer therapy and prevention

Nat Med. 2001 May;7(5):548-52. doi: 10.1038/87872.


The recent completion of the human genome sequence has raised great hopes for the discovery of new breast cancer therapies based on newly-discovered genes linked to breast cancer development and progression. Here we describe breast cancer therapies that have emerged from gene-based scientific efforts over the past 20 years and that are now approved for clinical testing or treatment.

Publication types

  • Review

MeSH terms

  • Angiogenesis Inhibitors / pharmacology
  • Angiogenesis Inhibitors / therapeutic use
  • Breast Neoplasms / blood supply
  • Breast Neoplasms / drug therapy
  • Breast Neoplasms / genetics*
  • Breast Neoplasms / prevention & control
  • Female
  • Genes, erbB-2*
  • Humans
  • Neovascularization, Pathologic / prevention & control


  • Angiogenesis Inhibitors