MAC5: Bayesian inference of phylogenetic trees from DNA sequences incorporating gaps

G McGuire; M C Denham; D J Balding

doi:10.1093/bioinformatics/17.5.479

MAC5: Bayesian inference of phylogenetic trees from DNA sequences incorporating gaps

Bioinformatics. 2001 May;17(5):479-80. doi: 10.1093/bioinformatics/17.5.479.

Authors

G McGuire¹, M C Denham, D J Balding

Affiliation

¹ Department of Applied Statistics, PO Box 240, University of Reading, Reading RG6 6FN, UK. gmcguire@hgmp.mrc.ac.uk

PMID: 11331243
DOI: 10.1093/bioinformatics/17.5.479

Abstract

MAC5 implements MCMC sampling of the posterior distribution of tree topologies from DNA sequences containing gaps by using a five state model of evolution (the four nucleotides and the gap character).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Algorithms
Bayes Theorem
Computational Biology
Models, Genetic
Phylogeny*
Sequence Analysis, DNA / statistics & numerical data*
Software*