Cell control by membrane-cytoskeleton adhesion

Nat Rev Mol Cell Biol. 2001 May;2(5):392-6. doi: 10.1038/35073095.


The rates of mechanochemical processes, such as endocytosis, membrane extension and membrane resealing after cell wounding, are known to be controlled biochemically, through interaction with regulatory proteins. Here, I propose that these rates are also controlled physically, through an apparently continuous adhesion between plasma membrane lipids and cytoskeletal proteins.

Publication types

  • Review

MeSH terms

  • Cell Adhesion / physiology
  • Cell Membrane / chemistry*
  • Cell Membrane / physiology*
  • Cytoskeleton / physiology*
  • Endocytosis / physiology
  • Eukaryotic Cells / cytology*
  • Models, Biological