Gray ramus communicans nerve block: novel treatment approach for painful osteoporotic vertebral compression fracture

South Med J. 2001 Apr;94(4):387-93.

Abstract

Background: Osteoporotic vertebral compression fracture (OVCF) is a common complication of osteoporosis in the aging population. Refractory chronic pain may develop, and few effective treatment options exist.

Methods: We retrospectively analyzed 52 cases in which gray ramus communicans nerve block was used for painful OVCF after failure of conservative analgesic therapy. All were office-based, fluoroscopically guided procedures; a combination of 2% lidocaine and 2% sterile triamcinolone diacetate (Aristocort) was injected on the gray ramus tract of the somatic nerve root corresponding with radiographically documented OVCF. Patient-reported and physician-reported pain scores, analgesic medication use, and overall patient satisfaction were measured. The average follow-up period was 9 months.

Results: A 1-point improvement in pain scores was reported by 92% of patients and 88% of physicians; a 4-point improvement was reported by 63% and 58%, respectively. No patients reported increased pain scores; physicians reported increases in two cases. Decreased analgesic requirement was documented in 42%. Patient satisfaction was "high" in 50% and "medium" in 25%. No procedural complications occurred.

Conclusion: Prompt and sustained improvements in all parameters, especially pain scores, support widespread clinical application of this safe effective and cost-effective therapy.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Anesthetics, Local*
  • Anti-Inflammatory Agents*
  • Drug Combinations
  • Female
  • Fluoroscopy / methods*
  • Fluoroscopy / psychology
  • Fractures, Spontaneous / diagnostic imaging
  • Fractures, Spontaneous / etiology*
  • Fractures, Spontaneous / psychology
  • Fractures, Spontaneous / therapy*
  • Humans
  • Intervertebral Disc / innervation*
  • Lidocaine*
  • Male
  • Middle Aged
  • Nerve Block / methods*
  • Nerve Block / psychology
  • Osteoporosis / complications*
  • Osteoporosis / psychology
  • Pain / diagnosis
  • Pain / etiology*
  • Pain Management*
  • Pain Measurement
  • Patient Satisfaction
  • Radiography, Interventional / methods*
  • Radiography, Interventional / psychology
  • Retrospective Studies
  • Spinal Fractures / diagnostic imaging
  • Spinal Fractures / etiology*
  • Spinal Fractures / psychology
  • Spinal Fractures / therapy*
  • Treatment Outcome
  • Triamcinolone*

Substances

  • Anesthetics, Local
  • Anti-Inflammatory Agents
  • Drug Combinations
  • Triamcinolone
  • Lidocaine