Is there a difference between women and men in characteristics and outcome after in hospital cardiac arrest?

Resuscitation. 2001 Apr;49(1):15-23. doi: 10.1016/s0300-9572(00)00342-7.

Abstract

Aim: To describe the characteristics and outcome among patients suffering from an in-hospital cardiac arrest in women and men.

Methods: All patients who suffered an in-hospital cardiac arrest during a 4 year period in Sahlgrenska Hospital Göteborg, Sweden, where the cardiopulmonary resuscitation (CPR) team was called, were recorded and described prospectively in terms of characteristics and outcome.

Results: There were 557 patients suffering in-hospital cardiac arrest in whom the CPR-team was alerted. Among them, 217 (39%) were women. Women differed from men having a lower prevalence of earlier myocardial infarction, angina pectoris, renal disease and a higher prevalence of rheumatic disease. In terms of aetiology of the cardiac arrest, 47% men and 48% women were judged to have had a confirmed or possible AMI. More men than women were found in ventricular fibrillation/ventricular tachycardia (VF/VT) (57 vs. 41%; P<0.001), whereas more women were found in pulseless electrical activity (30 vs. 15%; P<0.0001). Cerebral performance categories (CPC)-score at discharge did not differ between men and women. Among women, 36.4% survived to discharge as compared with 38.0% among men (NS). Survival from VF/VT was 64.3% in women and 52.7% in men (NS). When correcting for dissimilarities at baseline, the adjusted odd ratio for being discharged alive from hospital among women as compared with men was 1.66 (95% confidence limit 1.06-2.62; P=0.028).

Conclusion: Thirty nine percent of patients suffering in-hospital cardiac arrest for whom the CPR-team was alerted, were women. Women were less frequently found in VF/VT than men. After correcting for dissimilarities at baseline, female gender was associated with a small improvement in survival.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cardiopulmonary Resuscitation
  • Coronary Disease / epidemiology
  • Female
  • Heart Arrest / epidemiology*
  • Hospitalization
  • Humans
  • Male
  • Prognosis
  • Prospective Studies
  • Retrospective Studies
  • Sex Factors
  • Survival Analysis
  • Survival Rate
  • Tachycardia, Ventricular / epidemiology
  • Time Factors
  • Treatment Outcome
  • Ventricular Fibrillation / epidemiology