Differences in the gut bacterial flora of healthy and milk-hypersensitive adults, as measured by fluorescence in situ hybridization

FEMS Immunol Med Microbiol. 2001 Apr;30(3):217-21. doi: 10.1111/j.1574-695X.2001.tb01573.x.

Abstract

We enumerated the predominant gut genera from fecal samples of nine healthy and eight milk-hypersensitive adults both before and after 4 weeks Lactobacillus rhamnosus GG (LGG) supplementation. The anaerobic intestinal microflora of milk-hypersensitive adults was found to resemble that of healthy adults. LGG-consumption resulted in a significant increase in the number of bifidobacteria in healthy but not in milk-hypersensitive subjects, as well as a general increase in bacterial numbers in all other bacterial genera tested in both groups. In conclusion, the composition of the gut microbiota in milk-hypersensitive adults appears to be normal. LGG may have potential in reinforcing the endogenous flora.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Bacteria, Anaerobic / growth & development
  • Bacteria, Anaerobic / isolation & purification*
  • Bifidobacterium / isolation & purification
  • Feces / microbiology*
  • Female
  • Humans
  • In Situ Hybridization, Fluorescence
  • Lactobacillus / growth & development
  • Lactobacillus / isolation & purification
  • Male
  • Milk Hypersensitivity / microbiology*
  • Probiotics / administration & dosage