Update in podocyte biology

Curr Opin Nephrol Hypertens. 2001 May;10(3):331-40. doi: 10.1097/00041552-200105000-00006.


Knowledge of podocyte biology is growing rapidly. Podocytes are crucially involved in most hereditary diseases affecting the glomerulus, which all exhibit podocyte-specific defects, that is, foot process effacement and protein leakage. Efforts to understand molecular mechanisms causing these derangements are increasingly successful and will allow a better targeting of interventions to halt the progression of chronic renal disease.

Publication types

  • Review

MeSH terms

  • Epithelial Cells / pathology
  • Epithelial Cells / physiology
  • Humans
  • Kidney Diseases* / etiology
  • Kidney Diseases* / pathology
  • Kidney Diseases* / physiopathology
  • Kidney Glomerulus* / pathology
  • Kidney Glomerulus* / physiology