Diamondback moth compensatory consumption of protease inhibitor-transformed plants

Mol Ecol. 2001 Apr;10(4):1069-74. doi: 10.1046/j.1365-294x.2001.01239.x.

Abstract

Prior study of the effect of protease inhibitors (PIs) on diamondback moths suggests that moths are resistant to them, so PIs represent an ineffective defence against moths. However, our data suggest that diamondback moths do suffer lower growth rates when they consume plants transformed with potato protease inhibitor (PI2), but that effect is hidden by compensatory consumption. Plants, instead of gaining an advantage by lowering the insect growth rate, suffer a disadvantage as moths consume more tissue to mitigate the effect. Furthermore, PI2, when used in conjunction with another transgenic pesticidal protein, Bt (from Bacillus thuringiensis) counteracts the effectiveness of Bt at protecting plant tissue. Thus, transgenic PIs are not only less effective than previously thought in protecting Brassica plants from diamondback moths, they may actually lead to increased plant damage by the moths.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Analysis of Variance
  • Animals
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism*
  • Bacterial Toxins*
  • Brassica / genetics
  • Brassica / physiology*
  • Endotoxins / genetics
  • Endotoxins / metabolism*
  • Hemolysin Proteins
  • Moths / growth & development
  • Moths / physiology*
  • Pest Control, Biological
  • Plant Leaves / anatomy & histology
  • Plant Leaves / chemistry
  • Plant Proteins / genetics
  • Plant Proteins / metabolism
  • Plants, Genetically Modified
  • Protease Inhibitors / metabolism*

Substances

  • Bacterial Proteins
  • Bacterial Toxins
  • Endotoxins
  • Hemolysin Proteins
  • Plant Proteins
  • Protease Inhibitors
  • insecticidal crystal protein, Bacillus Thuringiensis
  • proteinase inhibitor II protein, plant