o,p'DDD therapy in invasive adrenocortical carcinoma

Ann Intern Med. 1975 May;82(5):677-9. doi: 10.7326/0003-4819-82-5-677.

Abstract

Invasive adrenocortical carcinoma was diagnosed in two patients, 3 1/2 and 69 years of age, respectively. Therapy with o,p'DDD was begun immediately, and the patients have survived 4 1/12 and 7 9/12 years, respectively. The prolonged survival represents possible "cure" of inoperable disease following early initiation of therapy.

MeSH terms

  • Adrenal Cortex*
  • Adrenal Gland Neoplasms / drug therapy*
  • Adrenal Gland Neoplasms / surgery
  • Adrenal Glands*
  • Aged
  • Carcinoma / drug therapy*
  • Carcinoma / surgery
  • Child, Preschool
  • Dichlorodiphenyldichloroethane / administration & dosage
  • Dichlorodiphenyldichloroethane / therapeutic use*
  • Humans
  • Male
  • Mitotane / administration & dosage
  • Mitotane / therapeutic use*

Substances

  • Mitotane
  • Dichlorodiphenyldichloroethane