[Cerebellar ataxia due to hypothyroidism in adults (case report)]

Dtsch Med Wochenschr. 1975 Jul 11;100(28):1504-6. doi: 10.1055/s-0028-1106608.
[Article in German]


Cerebellar ataxia was diagnosed in a 62-year-old woman, its signs regressing almost completely within six weeks during treatment with thyroxine and triiodothyronine. The cause of cerebellar ataxia in association with hypothyroidism remains unknown. No typical morphological changes in the cerebellum have been described. It is assumed that a thyrogenic, specific metabolic factor is responsible which aggravates already existing non-specific cerebellar changes. The prognosis is very good. On the other hand, cerebellar ataxia resulting from congenital hypothyroidism has typical histological cerebellar changes and prognosis is very poor unless thyroid treatment is started soon after birth.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Cerebellar Ataxia / diagnosis
  • Cerebellar Ataxia / drug therapy
  • Cerebellar Ataxia / etiology*
  • Congenital Hypothyroidism
  • Female
  • Humans
  • Hypothyroidism / complications*
  • Hypothyroidism / diagnosis
  • Hypothyroidism / drug therapy
  • Middle Aged
  • Prognosis
  • Thyroxine / therapeutic use
  • Triiodothyronine / therapeutic use


  • Triiodothyronine
  • Thyroxine