doi: 10.1038/88836.
Association analysis of NOTCH4 loci in schizophrenia using family and population-based controls
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- PMID: 11381257
- DOI: 10.1038/88836
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Association analysis of NOTCH4 loci in schizophrenia using family and population-based controls
Nat Genet.
2001 Jun.
Abstract
A genetic association between NOTCH4 and schizophrenia has previously been proposed. Unsing all markers previously shown to be associated, we found no evidence for such in three independent family-based samples (n=519 parent-offspring trios), and a case-control sample derived from the same ethnic background as the original observation. These data strongly suggest that NOTCH4 is not a significant susceptibility allele for schizophrenia.
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