Review
doi: 10.3810/pgm.2001.05.931.
Preventing gastrointestinal complications of NSAIDs. Risk factors, recent advances, and latest strategies
Affiliations
- PMID: 11381661
- DOI: 10.3810/pgm.2001.05.931
Item in Clipboard
Review
Preventing gastrointestinal complications of NSAIDs. Risk factors, recent advances, and latest strategies
Postgrad Med.
2001 May.
Abstract
In the United States, gastrointestinal complications induced by nonsteroidal anti-inflammatory drugs (NSAIDs) cause more than 100,000 hospitalizations and an estimated 16,500 deaths annually. Because serious gastrointestinal events can occur without warning, prevention measures must not rely on warning signs alone. This article discusses the epidemiology of NSAID-induced toxic episodes, reviews the risk factors for these occurrences, and offers strategies for minimizing the risk among long-term NSAID users.
Similar articles
-
Arthritis treatment in Hong Kong--cost analysis of celecoxib versus conventional NSAIDS, with or without gastroprotective agents.Aliment Pharmacol Ther. 2002 Dec;16(12):2089-96. doi: 10.1046/j.1365-2036.2002.01376.x. Aliment Pharmacol Ther. 2002. PMID: 12452942
-
The relative efficacies of gastroprotective strategies in chronic users of nonsteroidal anti-inflammatory drugs.Gastroenterology. 2008 Apr;134(4):937-44. doi: 10.1053/j.gastro.2008.01.010. Epub 2008 Jan 11. Gastroenterology. 2008. PMID: 18294634
-
The cost effectiveness of rofecoxib and celecoxib in patients with osteoarthritis or rheumatoid arthritis.Arthritis Rheum. 2003 Jun 15;49(3):283-92. doi: 10.1002/art.11121. Arthritis Rheum. 2003. PMID: 12794781
-
Celecoxib versus a non-selective NSAID plus proton-pump inhibitor: what are the considerations?J Pain Palliat Care Pharmacother. 2006;20(4):11-32. J Pain Palliat Care Pharmacother. 2006. PMID: 17182503 Review.
-
Reducing NSAID-induced gastrointestinal complications.Drug Ther Bull. 2011 Feb;49(2):18-21; quiz i-ii. doi: 10.1136/dtb.2011.02.0007. Drug Ther Bull. 2011. PMID: 21304164 Review.
Cited by
-
The Combined Effect of Curcumin and Crocin on the Reduction of Inflammatory Responses in Arthritic Rats.Curr Med Chem. 2024;31(28):4562-4577. doi: 10.2174/0929867330666230409003744. Curr Med Chem. 2024. PMID: 37031388
-
Engaging Pharmacists to Crowdsource a Fine-grained Medication Risk Scale: An Initial Measurement Study Using Paired Comparisons of Medications.AMIA Annu Symp Proc. 2020 Mar 4;2019:428-437. eCollection 2019. AMIA Annu Symp Proc. 2020. PMID: 32308836 Free PMC article.
-
New formulation of ibuprofen on absorption-rate: A comparative bioavailability study in healthy volunteers.Caspian J Intern Med. 2019 Spring;10(2):150-155. doi: 10.22088/cjim.10.2.150. Caspian J Intern Med. 2019. PMID: 31363393 Free PMC article.
-
Rosmarinic Acid Enriched Fraction from Perilla frutescens Leaves Strongly Protects Indomethacin-Induced Gastric Ulcer in Rats.Biomed Res Int. 2019 Mar 4;2019:9514703. doi: 10.1155/2019/9514703. eCollection 2019. Biomed Res Int. 2019. PMID: 30949513 Free PMC article.
-
Chronic low back pain: a mini-review on pharmacological management and pathophysiological insights from clinical and pre-clinical data.Inflammopharmacology. 2018 May 12. doi: 10.1007/s10787-018-0493-x. Online ahead of print. Inflammopharmacology. 2018. PMID: 29754321 Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
