Importance of dihydropyrimidine dehydrogenase (DPD) deficiency in patients exhibiting toxicity following treatment with 5-fluorouracil

Adv Enzyme Regul. 2001;41:151-7. doi: 10.1016/s0065-2571(00)00011-x.
No abstract available

MeSH terms

  • Antimetabolites, Antineoplastic / therapeutic use*
  • Antimetabolites, Antineoplastic / toxicity*
  • Dihydrouracil Dehydrogenase (NADP)
  • Female
  • Fluorouracil / therapeutic use*
  • Fluorouracil / toxicity*
  • Humans
  • Leukocytes, Mononuclear / metabolism
  • Male
  • Oxidoreductases / deficiency*
  • Phenotype

Substances

  • Antimetabolites, Antineoplastic
  • Oxidoreductases
  • Dihydrouracil Dehydrogenase (NADP)
  • Fluorouracil