The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting

Adv Enzyme Regul. 2001:41:189-207. doi: 10.1016/s0065-2571(00)00013-3.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Area Under Curve
  • Blood Pressure
  • Carcinoma, Hepatocellular / blood supply
  • Carcinoma, Hepatocellular / pathology
  • Drug Delivery Systems*
  • Humans
  • Liver / metabolism
  • Liver Neoplasms / blood supply
  • Liver Neoplasms / pathology
  • Models, Biological
  • Neoplasms / blood supply*
  • Neoplasms / therapy*
  • Permeability*
  • Polymers / therapeutic use
  • Time Factors
  • Tissue Distribution
  • Veins / metabolism

Substances

  • Polymers