Apoptosis signaling pathways mediated by cyclooxygenase-2 inhibitors in prostate cancer cells

Adv Enzyme Regul. 2001;41:221-35. doi: 10.1016/s0065-2571(00)00015-7.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Apoptosis*
  • Calcium / metabolism
  • Celecoxib
  • Cell Cycle
  • Cell Survival
  • Cyclooxygenase 2
  • Cyclooxygenase 2 Inhibitors
  • Cyclooxygenase Inhibitors / pharmacology
  • DNA Fragmentation
  • Dose-Response Relationship, Drug
  • Enzyme Inhibitors / pharmacology
  • Flow Cytometry
  • Humans
  • Isoenzymes / antagonists & inhibitors*
  • Isoenzymes / metabolism*
  • Lactones / pharmacology
  • Male
  • Membrane Proteins
  • Models, Chemical
  • Nitrobenzenes / pharmacology
  • Phosphatidylinositol 3-Kinases / metabolism
  • Prostaglandin-Endoperoxide Synthases / metabolism*
  • Prostatic Neoplasms / metabolism*
  • Proto-Oncogene Proteins c-bcl-2 / metabolism
  • Pyrazoles
  • Signal Transduction*
  • Sulfonamides / pharmacology
  • Sulfones
  • Thiophenes / pharmacology
  • Time Factors
  • Tumor Cells, Cultured
  • Tumor Suppressor Protein p53 / metabolism

Substances

  • Cyclooxygenase 2 Inhibitors
  • Cyclooxygenase Inhibitors
  • Enzyme Inhibitors
  • Isoenzymes
  • Lactones
  • Membrane Proteins
  • Nitrobenzenes
  • Proto-Oncogene Proteins c-bcl-2
  • Pyrazoles
  • Sulfonamides
  • Sulfones
  • Thiophenes
  • Tumor Suppressor Protein p53
  • rofecoxib
  • N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide
  • DuP 697
  • Cyclooxygenase 2
  • PTGS2 protein, human
  • Prostaglandin-Endoperoxide Synthases
  • Phosphatidylinositol 3-Kinases
  • Celecoxib
  • Calcium