Wilson's disease in pregnancy: five successful consecutive pregnancies of the same woman

B Furman; A Bashiri; A Wiznitzer; O Erez; G Holcberg; M Mazor

doi:10.1016/s0301-2115(00)00456-5

Wilson's disease in pregnancy: five successful consecutive pregnancies of the same woman

Eur J Obstet Gynecol Reprod Biol. 2001 Jun;96(2):232-4. doi: 10.1016/s0301-2115(00)00456-5.

Authors

B Furman¹, A Bashiri, A Wiznitzer, O Erez, G Holcberg, M Mazor

Affiliation

¹ Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

PMID: 11384817
DOI: 10.1016/s0301-2115(00)00456-5

Abstract

Wilson's disease is an autosomal recessive disorder of copper metabolism characterized mainly by liver cirrhosis and neurological disorders. Appropriate treatment with chelating agents allows normal fertility function. We report five consecutive successful pregnancies of the same woman, treated in the high-risk unit at our medical center. The management dilemmas and treatment options are discussed.

Publication types

Case Reports

MeSH terms

Alanine Transaminase / blood
Apgar Score
Aspartate Aminotransferases / blood
Chelating Agents / therapeutic use
Female
Gestational Age
Hepatolenticular Degeneration / drug therapy*
Humans
Infant, Newborn
Penicillamine / therapeutic use
Platelet Count
Pregnancy
Pregnancy Complications*
Pregnancy Outcome*
Risk Factors

Substances

Chelating Agents
Aspartate Aminotransferases
Alanine Transaminase
Penicillamine