Prevalence of renal disease in asymptomatic heroin addicts

Arch Intern Med. 1975 Apr;135(4):535-7.


Renal function was studied in 145 asymptomatic male heroin addicts admitted to a methadone detoxification program. The mean duration of addiction was ten years. Three patients had protein excretion greater than 150 mg/24 hr; in one of these, membranous glomerulonephritis was found. All except one had normal creatinine clearance. Hypertension was present in 2.7%. This study does not support the concept that heroin addiction is associated with a high prevalence of renal disease.

MeSH terms

  • Chicago
  • Creatine / urine
  • Evaluation Studies as Topic
  • Heroin Dependence / complications*
  • Heroin Dependence / drug therapy
  • Humans
  • Hypertension / epidemiology
  • Inactivation, Metabolic
  • Kidney Diseases / diagnosis
  • Kidney Diseases / epidemiology*
  • Methadone / therapeutic use
  • Proteinuria


  • Creatine
  • Methadone