Interpretation of Complex Forensic DNA Mixtures

Croat Med J. 2001 Jun;42(3):244-6.

Abstract

Forensic evidentiary samples routinely contain DNA from multiple contributors. The interpretation of these mixtures can be a challenging task for the DNA scientist. Several approaches are discussed (no calculation- qualitative statement; probability of exclusion; likelihood ratio estimates; presumptive genotype assignment based on peak heights), which have been employed to assess the significance of an inclusion/match when DNA mixtures have been detected in casework samples. These statistical approaches are discussed in light of technical challenges that can arise when evaluating evidentiary samples.

Publication types

  • Review

MeSH terms

  • Criminology
  • DNA / analysis*
  • DNA Fingerprinting / methods*
  • Data Interpretation, Statistical
  • Expert Testimony / standards
  • Female
  • Forensic Medicine / methods*
  • Forensic Medicine / standards*
  • Genotype
  • Humans
  • Likelihood Functions
  • Male
  • Polymerase Chain Reaction / methods*
  • Sensitivity and Specificity
  • Specimen Handling
  • United States

Substances

  • DNA