Abstract
A new A gamma chain haemoglobin variant, haemoglobin F Victoria Jubilee, with an electrophoretic mobility slightly anodal to haemoglobin F Port Royal, was found in a Jamaican infant. The amino acid residue substitution of 80 Aspartic Acid leads to Tyrosine was associated with alanine in position 136. Haemoglobin F Victoria Jubilee constituted about 7.0 percent of the total haemoglobin F.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Amino Acid Sequence
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Amino Acids / analysis
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Aspartic Acid / analysis
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Chromatography, Ion Exchange
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Electrophoresis, Starch Gel
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Female
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Hemoglobins
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Hemoglobins, Abnormal*
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Humans
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Infant, Newborn
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Jamaica
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Pedigree
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Peptide Fragments / analysis
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Trypsin
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Tyrosine / analysis
Substances
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Amino Acids
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Hemoglobins
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Hemoglobins, Abnormal
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Peptide Fragments
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Aspartic Acid
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Tyrosine
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Trypsin