Control of an outbreak of infection due to extended-spectrum beta-lactamase--producing Escherichia coli in a liver transplantation unit

Clin Infect Dis. 2001 Jul 1;33(1):126-8. doi: 10.1086/320882. Epub 2001 May 23.


We report an outbreak of infection due to genotypically identical extended-spectrum beta-lactamase--producing Escherichia coli among patients in a liver transplantation unit. Control of the outbreak was achieved by a combination of contact isolation, feedback on hand hygiene, and gut decontamination with an orally administered fluoroquinolone. These interventions led to abrupt curtailment of the outbreak.

MeSH terms

  • Disease Outbreaks*
  • Escherichia coli / enzymology*
  • Escherichia coli Infections / epidemiology
  • Escherichia coli Infections / microbiology*
  • Escherichia coli Infections / prevention & control
  • Hospital Units
  • Humans
  • Infection Control* / methods*
  • Liver Transplantation*
  • beta-Lactamases / metabolism*


  • beta-Lactamases