Intracellular survival strategies of mutualistic and parasitic prokaryotes

Trends Microbiol. 2001 Jun;9(6):267-73. doi: 10.1016/s0966-842x(01)02040-6.


Endosymbiotic bacteria closely related to mammalian pathogens are widespread in invertebrates. Mutualistic and parasitic bacteria-host interactions on the various evolutionary levels apparently involve similar factors, indicating that relevant genetic information developed early in evolution. The detailed characterization of symbiotic interactions of bacteria with non-mammalian hosts should provide profound insights into the basic mechanisms of bacteria-host interactions and their evolution.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Bacterial Physiological Phenomena*
  • Biological Evolution*
  • Host-Parasite Interactions
  • Humans
  • Parasites
  • Prokaryotic Cells / physiology
  • Symbiosis / physiology*