Abstract
This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Nobuhiro Sato and Kai O. Lindros. The presentations were (1) Sex differences in ethanol pharmacokinetics, by E. Baraona; (2) Estrogen regulates the sensitivity to endotoxin in hepatic Kupffer cells, by K. Ikejima; (3) Sex difference in alcohol-related organ injury, by E. Mezey; (4) Aggravated ethanol-induced liver injury in female rats: Protection by the antiestrogen toremifene, by Harri A. Järveläinen; and (5) Alcohol metabolism in Asian subjects: Sex differences and flushing response, by V. A. Ramchandani.
MeSH terms
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Alcohol Dehydrogenase / metabolism*
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Alcohol-Related Disorders / ethnology
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Alcohol-Related Disorders / metabolism*
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Animals
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Brain Damage, Chronic / chemically induced
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Brain Damage, Chronic / metabolism
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Central Nervous System Depressants / pharmacokinetics*
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Estrogen Receptor Modulators / therapeutic use
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Ethanol / pharmacokinetics*
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Fatty Liver, Alcoholic / drug therapy
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Fatty Liver, Alcoholic / metabolism
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Female
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Flushing / metabolism
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Gonadal Steroid Hormones / metabolism*
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Heart Diseases / metabolism
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Humans
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Kupffer Cells / drug effects
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Kupffer Cells / metabolism
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Male
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Selective Estrogen Receptor Modulators / therapeutic use
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Sex Factors
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Toremifene / therapeutic use
Substances
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Central Nervous System Depressants
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Estrogen Receptor Modulators
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Gonadal Steroid Hormones
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Selective Estrogen Receptor Modulators
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Ethanol
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Toremifene
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Alcohol Dehydrogenase