Sex difference in alcohol-related organ injury

Alcohol Clin Exp Res. 2001 May;25(5 Suppl ISBRA):40S-45S. doi: 10.1097/00000374-200105051-00007.

Abstract

This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Nobuhiro Sato and Kai O. Lindros. The presentations were (1) Sex differences in ethanol pharmacokinetics, by E. Baraona; (2) Estrogen regulates the sensitivity to endotoxin in hepatic Kupffer cells, by K. Ikejima; (3) Sex difference in alcohol-related organ injury, by E. Mezey; (4) Aggravated ethanol-induced liver injury in female rats: Protection by the antiestrogen toremifene, by Harri A. Järveläinen; and (5) Alcohol metabolism in Asian subjects: Sex differences and flushing response, by V. A. Ramchandani.

Publication types

  • Review

MeSH terms

  • Alcohol Dehydrogenase / metabolism*
  • Alcohol-Related Disorders / ethnology
  • Alcohol-Related Disorders / metabolism*
  • Animals
  • Brain Damage, Chronic / chemically induced
  • Brain Damage, Chronic / metabolism
  • Central Nervous System Depressants / pharmacokinetics*
  • Estrogen Receptor Modulators / therapeutic use
  • Ethanol / pharmacokinetics*
  • Fatty Liver, Alcoholic / drug therapy
  • Fatty Liver, Alcoholic / metabolism
  • Female
  • Flushing / metabolism
  • Gonadal Steroid Hormones / metabolism*
  • Heart Diseases / metabolism
  • Humans
  • Kupffer Cells / drug effects
  • Kupffer Cells / metabolism
  • Male
  • Selective Estrogen Receptor Modulators / therapeutic use
  • Sex Factors
  • Toremifene / therapeutic use

Substances

  • Central Nervous System Depressants
  • Estrogen Receptor Modulators
  • Gonadal Steroid Hormones
  • Selective Estrogen Receptor Modulators
  • Ethanol
  • Toremifene
  • Alcohol Dehydrogenase