[Effect of factors from the Chernobyl exclusion zone on the level of cytochrome P-450 in mouse liver microsomes]

L G Glushakova; O V Maksimchuk; I M Danko; O F Siniuk; N A Chashchin

[Effect of factors from the Chernobyl exclusion zone on the level of cytochrome P-450 in mouse liver microsomes]

Ukr Biokhim Zh (1999). 2000 Nov-Dec;72(6):63-6.

[Article in Russian]

Authors

L G Glushakova¹, O V Maksimchuk, I M Danko, O F Siniuk, N A Chashchin

Affiliation

¹ Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine.

PMID: 11392787

Abstract

The data concerning the influence of Chernobyl exclusive zone factors on cytochrome P-450 relative contents in liver microsome fractions of Balb/c, CC57W/Mv and C57 Black mice are submitted in this work Reliable diminishing of liver P-450 relative concentration in experimental animals, compared with respective isogenic control groups is shown to be varying depending on the mouse line and sex.

Publication types

English Abstract

MeSH terms

Animals
Cytochrome P-450 Enzyme System / metabolism*
Female
Male
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Microsomes, Liver / enzymology
Microsomes, Liver / radiation effects*
Power Plants*
Radioactive Hazard Release*
Species Specificity
Ukraine

Substances

Cytochrome P-450 Enzyme System