Surgical treatment of hemangioblastomas with presurgical endovascular embolization

Neurol Med Chir (Tokyo). 2001 May;41(5):246-51; discussion 251-2. doi: 10.2176/nmc.41.246.

Abstract

The usefulness of presurgical embolization of hemangioblastomas was evaluated retrospectively in eight of 30 operations performed on eight of 27 consecutive patients with histologically verified hemangioblastoma. All tumors had over 3.5 cm maximum diameter of the solid mass. Presurgical embolization achieved 100% embolization in one case, 95% to 80% in two, 70% to 50% in two, and less than 50% in three. Total obliteration was obtained only in one case with a single feeding artery. No permanent neurological deficits developed after embolization, but cerebellar infarction occurred in one patient. The surgery was definitely easier than expected in three cases with 80% or more obliteration of tumors. Tumor swelling and cerebellar hematoma occurred during operation in one case with 70% tumor embolization and another case with less than 50%. Blood transfusion during operation was carried out in two cases with less than 50% tumor embolization. The clinical outcome was good recovery in one case, moderate disability in five, and severe disability in two. The reasons for residual neurological deficits were operation and meningitis in one patient, operative and preoperative symptoms in two, and residual preoperative symptoms in four. Neurological deterioration after surgery occurred in three patients with tumor embolization of less than 50%. Partial embolization of hemangioblastomas does not reduce operative complications or morbidity, unless almost complete embolization is achieved, which is not so easy.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cerebellar Neoplasms / diagnosis
  • Cerebellar Neoplasms / surgery
  • Cerebellar Neoplasms / therapy*
  • Cerebellum / blood supply
  • Cerebellum / diagnostic imaging
  • Cerebral Angiography
  • Cerebral Arteries / diagnostic imaging
  • Embolization, Therapeutic / methods*
  • Female
  • Hemangioblastoma / diagnosis
  • Hemangioblastoma / surgery
  • Hemangioblastoma / therapy*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neurosurgical Procedures / methods*
  • Preoperative Care*