Allergic contact sensitization in an adult Danish population: two cross-sectional surveys eight years apart (the Copenhagen Allergy Study)

Acta Derm Venereol. Jan-Feb 2001;81(1):31-4. doi: 10.1080/000155501750208155.

Abstract

In 1990 and 1998 15-41-year-old people were patch-tested in 2 cross-sectional studies of random samples of the population in the western part of Copenhagen County, Denmark. In 1990, 290 subjects and in 1998, 469 subjects were patch-tested. The participation rates were 69% and 51%, respectively. Contact sensitivity to one or more haptens was found in 15.9% and 18.6% in 1990 and 1998, respectively. Nickel sensitivity is still the most common contact sensitivity. The risk of contact sensitivity to the cosmetic-related haptens included in the series (formaldehyde was not included) increased significantly from 2.4% in 1990 to 5.8% in 1998 (odds ratio 2.44, 95% confidence interval 1.04-5.73). The prevalence of contact sensitivity to cosmetic-related allergens has been doubled between 1990 and 1998.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Allergens / pharmacology*
  • Confidence Intervals
  • Cross-Sectional Studies
  • Denmark / epidemiology
  • Dermatitis, Allergic Contact / diagnosis*
  • Dermatitis, Allergic Contact / epidemiology
  • Dermatitis, Allergic Contact / immunology
  • Female
  • Haptens
  • Humans
  • Hypersensitivity / diagnosis*
  • Hypersensitivity / epidemiology
  • Hypersensitivity / immunology*
  • Incidence
  • Male
  • Odds Ratio
  • Patch Tests / methods*
  • Population Surveillance
  • Sampling Studies
  • Sensitivity and Specificity
  • Sex Distribution
  • Time Factors

Substances

  • Allergens
  • Haptens