Hughes syndrome associated with varicella infection

Rheumatol Int. 2001 May;20(4):167-8. doi: 10.1007/s002960000086.


We report a case of Hughes syndrome 1 week after the occurrence of chickenpox. The patient presented with the clinical picture of acute right iliofemoropopliteal deep vein thrombosis. IgM and IgG anticardiolipin (aCL) were both positive upon admission. The IgM aCL antibodies were still positive 6 weeks later, which suggests their role as a predisposing factor of deep vein thrombosis.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anticoagulants / therapeutic use
  • Chickenpox / complications*
  • Chickenpox / diagnosis*
  • Humans
  • Male
  • Phlebography
  • Prognosis
  • Risk Assessment
  • Syndrome
  • Thrombophlebitis / diagnostic imaging
  • Thrombophlebitis / drug therapy
  • Thrombophlebitis / etiology*
  • Treatment Outcome


  • Anticoagulants