Synaptic plasticity: rush hour traffic in the AMPA lanes

Curr Biol. 2001 Apr 3;11(7):R274-7. doi: 10.1016/s0960-9822(01)00137-3.

Abstract

Recent experiments indicate that modification of synaptic strength may involve rapid regulation of vesicular traffic on the postsynaptic side of the synapse. The specific vesicular trafficking route taken by postsynaptic receptors appears to depend on the stimulus.

MeSH terms

  • Glutamic Acid / metabolism
  • Neuronal Plasticity* / physiology
  • Receptors, AMPA / metabolism*
  • Receptors, N-Methyl-D-Aspartate / metabolism*
  • Synapses / physiology*
  • Synaptic Transmission*

Substances

  • Receptors, AMPA
  • Receptors, N-Methyl-D-Aspartate
  • Glutamic Acid