A case of malignant proliferating trichilemmoma of the scalp with multiple metastases

Korean J Intern Med. 2001 Mar;16(1):40-3. doi: 10.3904/kjim.2001.16.1.40.


We report a case of malignant proliferating trichilemmal tumor showing multiple distant metastases. The patient demonstrated a round mass in the right occipital area for 12 months and the lesion grew rapidly to assume 8 x 6.5 x 4 cm in diameter, with areas of superficial erosion and crusting within the recent 3 months. The entire lesion was removed with a wide surgical excision. It recurred on the neck area 4 months after excision and the lesion was removed with surgical resection again. There was evidence of multiple metastases on CNS and mediastinal lymph nodes after 6 months. The patient was treated with cisplatin and etoposide combination chemotherapy and a partial response was achieved.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Biopsy, Needle
  • Brain Neoplasms / pathology
  • Brain Neoplasms / secondary*
  • Brain Neoplasms / therapy
  • Combined Modality Therapy
  • Follow-Up Studies
  • Head and Neck Neoplasms / pathology*
  • Head and Neck Neoplasms / surgery
  • Head and Neck Neoplasms / therapy
  • Humans
  • Immunohistochemistry
  • Lymphatic Metastasis
  • Male
  • Neoplasms, Basal Cell / secondary*
  • Neoplasms, Basal Cell / therapy
  • Neurosurgical Procedures / methods
  • Reoperation
  • Scalp*
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / surgery
  • Skin Neoplasms / therapy
  • Tomography, X-Ray Computed