Pathogenicity and resistance islands of staphylococci

Microbes Infect. 2001 Jun;3(7):585-94. doi: 10.1016/s1286-4579(01)01414-9.

Abstract

Variable genetic elements including plasmids, transposons and prophages are involved in pathogenesis and antibiotic resistance, and are an important component of the staphylococcal genome. This review covers a set of newly described variable chromosomal elements, pathogenicity and resistance islands, carrying superantigen and resistance genes, especially toxic shock and methicillin resistance, respectively.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Toxins*
  • Base Sequence
  • Chromosomes, Bacterial / genetics
  • DNA, Bacterial / chemistry
  • Drug Resistance, Microbial / genetics
  • Enterotoxins / genetics
  • Enterotoxins / physiology
  • Evolution, Molecular
  • Genome, Bacterial
  • Humans
  • Methicillin Resistance / genetics
  • Microbial Sensitivity Tests
  • Molecular Sequence Data
  • Shock, Septic / microbiology
  • Staphylococcal Infections / drug therapy
  • Staphylococcal Infections / microbiology
  • Staphylococcus / drug effects
  • Staphylococcus / genetics*
  • Staphylococcus / immunology
  • Staphylococcus / pathogenicity
  • Superantigens / genetics
  • Superantigens / physiology

Substances

  • Anti-Bacterial Agents
  • Bacterial Toxins
  • DNA, Bacterial
  • Enterotoxins
  • Superantigens
  • enterotoxin F, Staphylococcal