Environmental and biological monitoring of occupational exposure to organic micropollutants in gasoline

Chemosphere. 2001 Jul;44(1):67-82. doi: 10.1016/s0045-6535(00)00364-7.


An exposure risk assessment of workers in a refinery production unit was undertaken. Gasoline and its main components were investigated through environmental and biological monitoring. Measured variables were environmental benzene, toluene, pentane and hexane; benzene and toluene in blood and urine; tt-MA (metabolite of benzene) in urine. Multivariate statistical analysis of the data showed that worker's exposure to the above substances fell within the limits specified by organisations such as ACGIH. Also, biological values complied with reference values (RV) for non-occupationally-exposed population. Different values of biological variables were determined by separating smokers from non-smokers: smokers had hematic and urinary benzene values significantly higher than non-smokers. During a 3-yr sampling, it was possible to identify a significant decrease of benzene in the workplace air and of hematic benzene for non-smokers. The most exposed department, one in which tank-lorries were loaded, needs further investigation and extended monitoring.

MeSH terms

  • Adult
  • Benzene / analysis*
  • Biomarkers / analysis
  • Carcinogens, Environmental*
  • Environmental Monitoring
  • Female
  • Gasoline*
  • Humans
  • Industry
  • Inhalation Exposure
  • Male
  • Occupational Exposure*
  • Risk Assessment
  • Smoking
  • Toluene / urine*
  • Workplace


  • Biomarkers
  • Carcinogens, Environmental
  • Gasoline
  • Toluene
  • Benzene