This case report describes the history, clinical signs and diagnosis of a pruritic skin disease in three sibling cats living the same household. Clinical signs consistent with pruritus (i.e. hair pulling, hair loss, excessive grooming and face rubbing) were first noted when the cats were 6 months of age. The cats were treated for a possible ear mite and/or flea infestation; there was no response to treatment and clinical signs progressed. Although the presence of pruritus in a multiple cat household suggested an infectious or contagious aetiology, none could be identified. There was no improvement in clinical signs after a 60-day flea control trial, three treatments of ivermectin, an 8-week restricted diet or removal from the home for 10 days. A diagnosis of feline atopy was made on the basis of elimination of other causes of pruritus, consistent history and clinical signs, a positive intradermal skin test and response to therapy.