Abstract
Microbes have developed a number of different strategies to utilize iron, which is a vital element for most organisms but not always readily available from the environment. Based on experimental studies and sequence analysis data, this article gives a short overview of ABC transporters related to iron uptake: components of three distinct families mediate the translocation of iron, siderophores, heme and vitamin B12 across the cytoplasmic membrane of bacteria.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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ATP-Binding Cassette Transporters / chemistry
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ATP-Binding Cassette Transporters / genetics
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ATP-Binding Cassette Transporters / metabolism*
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Cell Membrane / metabolism
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Conserved Sequence
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Escherichia coli / genetics
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Escherichia coli / metabolism
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Ferric Compounds / metabolism
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Heme / metabolism*
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Inosine Monophosphate / metabolism
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Iron / metabolism*
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Phylogeny
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Siderophores / metabolism*
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Substrate Specificity
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Vitamin B 12 / metabolism*
Substances
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ATP-Binding Cassette Transporters
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Ferric Compounds
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Siderophores
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Inosine Monophosphate
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Heme
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Iron
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Vitamin B 12