Bombardolides: new antifungal and antibacterial gamma-lactones from the coprophilous fungus Bombardioidea anartia
- PMID: 11421752
- DOI: 10.1021/np000617u
Bombardolides: new antifungal and antibacterial gamma-lactones from the coprophilous fungus Bombardioidea anartia
Abstract
Chemical studies of organic extracts from cultures of the coprophilous fungus Bombardioidea anartia have led to the discovery of bombardolides A--D (1--4), a series of new antifungal and antibacterial metabolites. Three of these metabolites (1--3) were obtained as inseparable pairs of geometric isomers. A new 3-substituted phenol (5) and the known compound asterriquinone B4 were also encountered. The structures of compounds 1--5 were determined by analysis of NMR and MS data.
Similar articles
-
Anserinones A and B: new antifungal and antibacterial benzoquinones from the coprophilous fungus Podospora anserina.J Nat Prod. 1997 Jun;60(6):629-31. doi: 10.1021/np970071k. J Nat Prod. 1997. PMID: 9214737
-
Antifungal and antibacterial metabolites from a sclerotium-colonizing isolate of Mortierella vinacea.J Nat Prod. 1999 Feb;62(2):386-8. doi: 10.1021/np980411h. J Nat Prod. 1999. PMID: 10075797
-
Sporovexins A-C and a new preussomerin analog: antibacterial and antifungal metabolites from the coprophilous fungus Sporormiella vexans.J Nat Prod. 1999 Apr;62(4):659-61. doi: 10.1021/np980563c. J Nat Prod. 1999. PMID: 10217738
-
Pseudodestruxins A and B: new cyclic depsipeptides from the coprophilous fungus Nigrosabulum globosum.J Nat Prod. 2001 May;64(5):555-8. doi: 10.1021/np000547r. J Nat Prod. 2001. PMID: 11374942
-
Decipinin A and decipienolides A and B: new bioactive metabolites from the coprophilous fungus Podospora decipiens.J Nat Prod. 2002 Jun;65(6):916-9. doi: 10.1021/np010575p. J Nat Prod. 2002. PMID: 12088438
Cited by
-
Aruncin B: Synthetic Studies, Structural Reassignment and Biological Evaluation.Chemistry. 2017 Nov 21;23(65):16525-16534. doi: 10.1002/chem.201702949. Epub 2017 Oct 30. Chemistry. 2017. PMID: 28815753 Free PMC article.
-
A surprising mechanistic "switch" in Lewis acid activation: a bifunctional, asymmetric approach to alpha-hydroxy acid derivatives.J Am Chem Soc. 2008 Dec 17;130(50):17085-94. doi: 10.1021/ja806818a. J Am Chem Soc. 2008. PMID: 19053448 Free PMC article.
-
One pot multi-component synthesis of novel functionalized pyrazolo furan-2(5H)-one derivatives: in vitro, DFT, molecular docking, and pharmacophore studies, as coronavirus inhibitors.Mol Divers. 2025 Apr;29(2):965-989. doi: 10.1007/s11030-024-10885-x. Epub 2024 Aug 22. Mol Divers. 2025. PMID: 39168959 Free PMC article.
-
Catalytic, asymmetric reactions of ketenes and ketene enolates.Tetrahedron. 2009 Aug 22;65(34):3771-6803. doi: 10.1016/j.tet.2009.05.079. Tetrahedron. 2009. PMID: 21494417 Free PMC article. No abstract available.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
