New diterpenes from Jatropha divaricata

R W Denton; W W Harding; C I Anderson; H Jacobs; S McLean; W F Reynolds

doi:10.1021/np010098a

New diterpenes from Jatropha divaricata

J Nat Prod. 2001 Jun;64(6):829-31. doi: 10.1021/np010098a.

Authors

R W Denton¹, W W Harding, C I Anderson, H Jacobs, S McLean, W F Reynolds

Affiliation

¹ Department of Chemistry, University of the West Indies, Mona, Kingston 7, Jamaica.

PMID: 11421758
DOI: 10.1021/np010098a

Abstract

Extracts of the stems of Jatropha divaricata have yielded the two new diterpenes ent-3 beta,14 alpha-hydroxypimara-7,9(11),15-triene-12-one (3) and the rearranged pimarane ent-15(13-->8)abeo-8 beta(ethyl)pimarane (4), which appears to be a new skeletal type. The rare cleistanthane diterpenes spruceanol (1) and cleistanthol (2) were also obtained.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Diterpenes / chemistry*
Diterpenes / isolation & purification
Euphorbiaceae / chemistry*
Jamaica
Magnetic Resonance Spectroscopy
Methylation
Plants, Medicinal / chemistry*

Substances

Diterpenes
ent-3 ,14 -hydroxypimara-7,9(11),15-triene-12-one